當(dāng)前位置:首頁 > 產(chǎn)品中心 > 抗體/抗原 > 一抗 > bsm-62731R腫瘤壞死因子α誘導(dǎo)蛋白8重組兔單抗
簡要描述:Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine-activated cultured cells. Expressed at low l
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